[Snowflakian]

It sucks, but at the same time they can release the most wanted figures again later.
Like comic boxsets during ironman 3, or avengers. So some of the obscures may end up in your collection later anyway.

Tigerstripe wolverine comes to mind as one you could skip and would always get, ditto to classic cyclops. I'm sure there have been many others and will be many more (the thing, mr. fantastic, the huamn torch, warpath, deadpool, Hawkeye, thor...).

A hands of the mandarin set during Avengers would rock too.
Mandarin, Ironman modular, scarlet witch, war machine, 90s US Agent, Energy form wonderman. (Based on fan demand, recognition, character representation, and rarity of figures +ease of mold retools.) Stuff like that would be an eventual no-brainer.

Or even West coast, with Mocking bird, Hawkeye, and whoever else.

If a shield movie happens, probably even a pack of commander rogers, osborn, and nick fury.