[Snowflakian]

War of Kings: Talon(darkhawk variant), Lilandra, Vulcan, Blackbolt, Crystal, Ronin the Accuser.

Future Foundation: Sue Richards, Reed Richards, Spider-man, and Ben grimm all in Future Foundation costumes. Throw in the kids for the 2 open slots.

Streets of Vengence(or some such urban title): Anti-Venom, Cloak, Dagger, Shadowland Daredevil, Black Cat, and Ghost Rider/Vengence/Ketch Ghost Rider.

Teaching the next Generation(two sets):
Avengers academy: Hazmat, Finesse, Mettle, Veil, Reptil, and Lightning Lad(yeah I forgot his name.)
Academy X: Surge, X-23, Rockslide, Hellion, Anole, Mercury.

Annihilators: Ikon, Quasar, Beta Ray Bill

Thanos Imperitive: Nova Prime, Starlord, Thanos

Fear Itself: Juggernaut, Hulk, Titania.

As for a playset.
I'd like to see the entrance of the Xavier institute, or Avengers mansion. I'd especially love to see a Helicarrier playset akin to the GI Joe mobile base that opens up to reveal the bridge.