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Welcome to the Toyark!

At the moment, Mattel doesn't have a set pattern or a particular list of who will be reissued, but you can be sure it will most likely be the more popular characters. Chances are you could see those three again sometime in the future. For those that they've already re-issued, it may be a long time before they come around again.

If you're really serious about jumping head-first into this line, my suggestion would be to get a Club Eternia subscription, as that will help with the current figures and you get a club exclusive for "free". Re-issues are still on you to pick up (since you may not want dupes). Although getting dupes would solve the whole "open it or not" problem.

For me personally, I'm a loose collector but I do have some things MIB and MISB. It usually depends on how many versions of the mold I already have (repacks, redecos or remolds) and how easy the packaging is to put back together once it's been opened. Like Snow said, imports are a lot easier to work with than domestic stuff (unless it's a convention or specialty shop exclusive).