[Snowflakian]

Wonderman + Scarlet Spider (iron spidey clones)
Bishop + Invisible Woman (Just a simplistic for and against pack)
Ricochet + Darkhawk (The Support group for heroes)
She-Hulk + Prodigy (Drunken Prodigy needs a lawyer...)
and Howard the Duck + Nova Prime (sidelines so to speak, Howard gets out of registering, and Nova and tony get in a spat too)
or
Nova Prime + Shield Agent (when they surrounded his house in CW)
SongBird + O'Grady Ant-Man (Thunderbolts)
Squirrel Girl + Grasshopper (GLI)
Cloak + Dagger
Maria Hill + Tony stark
Sharon Carter + Maskless Stever Rogers. (bonus if he has handcuffs)
Crossbones + Red Skull's daughter
or
Falcon + Crossbones
Winter Soldier + Red Skull's Daughter
Jessica Drew + Heady lady of SWORD.
Unmasked Spider-man + Unmasked IronMan

I can be happy with simplicity. Everything else I want is just about covered...
Cept for Mascot Suit Deadpool or mockingbird, but they're secret invasion.